drugset / Trial / NCT01364675
Primary Prevention of Cardiovascular Disease (CVD) in Pre-diabetic & Pre-hypertensive Subjects
Unknown
8900 enrolled
Ramathibodi Hospital
National Health Security Office, Thailand · collabThe Government Pharmaceutical Organization · collabUbon Ratchathani Public Health Office, Thailand · collab
RandomizedParallel-groupQuadruple-blindPrevention
Summary
The purpose of this study is to determine whether treating pre-diabetic \& pre-hypertensive individuals using multiple drugs intervention (anti-hypertensive drugs (i.e., ACEI) plus anti-glycemic drug (i.e., metformin) plus anti-hyperlipidemic drug (statin)) would lower Cardiovascular Disease (CVD) events.
Timeline
- Start
- 2012-01
- Primary completion
- 2016-07
- Completion
- 2016-12
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Enalapril | Other / unclassified | 10 mg | Oral |
| Subject | Metformin | Small molecule | 500 mg | Oral |
| Subject | Simvastatin | Small molecule | 10 mg | Oral |