drugset / Trial / NCT01626664

KW-0761 or Investigator's Choice in Subjects With Previously Treated Adult T-cell Leukemia-Lymphoma (ATL)

NCT01626664

Phase 2 Completed 71 enrolled Kyowa Kirin, Inc.
RandomizedParallel-groupOpen-labelTreatment

Summary

The purpose of this study is to estimate the overall response rate of subjects with relapsed or refractory Adult T-cell Leukemia-Lymphoma (ATL).

Timeline

Start
2012-06
Primary completion
2015-08
Completion
2018-02

Drugs

EvaluationDrugModalityDoseRoute
Subject Cisplatin Other / unclassified 100 mg/m2
Subject Cytarabine Small molecule 2000 mg/m2
Subject Dexamethasone Small molecule 40 mg
Comparator Gemcitabine Small molecule 1000 mg/m2
Subject Mogamulizumab Monoclonal antibody 1 mg/kg
Comparator Oxaliplatin Small molecule 100 mg/m2
Comparator Pralatrexate Other / unclassified 30 mg/m2