Hemodynamic Effects of Low Dose Spinal Anesthesia for Cesarean Section
Summary
We propose to study the effects on hemodynamics (blood pressure, cardiac output, and central venous pressure) of two doses of bupivacaine for spinal anesthesia during cesarean section: a higher dose of 12 mg to a lower dose of 4.5 mg. We will examine recovery times, incidence of hypotension, and compare pain control and maternal satisfaction during and after cesarean section. We hypothesize that low dose bupivacaine spinal anesthesia will provide equivalent anesthesia for cesarean section compared to conventional dose bupivacaine, with less hypotension, faster recovery time, and enhanced maternal satisfaction. Maternal satisfaction will be assessed by self-reported pain scores, incidence of nausea and vomiting, shivering, and ability to interact with baby in the OR.
Timeline
- Start
- 2013-11
- Primary completion
- 2014-06
- Completion
- 2015-12
Outcome
Outcome not reported
Stopped (Enrollment): “Difficulty with patient recruitment.”
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Bupivacaine | Other / unclassified | 4.5 mg | Other |
| Subject | Bupivacaine | Other / unclassified | 9 mg | Other |
| Background | Fentanyl | Other / unclassified | 15 ug | Other |
| Background | Morphine | Other / unclassified | 150 ug | Other |
Indications
No indication recorded.