drugset / Trial / NCT02226913

Effect of Sodium Bicarbonate Buffered Lidocaine on the Success of IAN Block of Teeth With Irreversible Pulpitis

NCT02226913

Phase 3 Completed 80 enrolled Masoud Saatchi
RandomizedSingle-groupDouble-blind

Summary

Buffering of local anesthetics (alkalinization) has been suggested in achieving pain control. The purpose of this prospective, randomized, double-blind study was to evaluate the effect of adding 0.6 mL 8.4% sodium bicarbonate to 3.0 mL 2% lidocaine with 1: 80,000 epinephrine on the success rate of IAN block for endodontic treatment of mandibular molars with symptomatic irreversible pulpitis.

Timeline

Start
2013-02
Primary completion
2013-09
Completion
2013-09

Drugs

EvaluationDrugModalityDoseRoute
Subject sodium bicarbonate Diagnostic / imaging agent 8.4 %
Background Epinephrine Other / unclassified
Background Lidocaine Other / unclassified 2 %

Indications

No indication recorded.