drugset / Trial / NCT02242201
Total Hip Arthroplasty (THA) Lumbar Plexus Verses Periarticular
RandomizedParallel-groupSingle-blindTreatment
Summary
Total hip arthroplasty is a one of the most commonly performed surgical procedures with increasing numbers anticipated over the next several decades. The purpose of this study was to find a better way to make patients comfortable after their hip surgery. Three different ways of providing pain relief were compared, a peripheral nerve block in the lower back outside of the spinal space (using bupivacaine, a numbing medicine), or injections around the hip joint with one of two different medicines, either Ropivacaine or Liposomal Bupivacaine (Exparel®).
Timeline
- Start
- 2014-09
- Primary completion
- 2016-09
- Completion
- 2016-09
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Comparator | Bupivacaine | Other / unclassified | 0.2 % | — |
| Comparator | Bupivacaine | Other / unclassified | 255 mg | — |
| Comparator | Ropivacaine | Other / unclassified | 200 mg | — |
| Comparator | Ropivacaine | Other / unclassified | 300 mg | — |
| Comparator | Ropivacaine | Other / unclassified | 400 mg | — |
| Comparator | Epinephrine | Other / unclassified | 100 ug | — |
| Comparator | Epinephrine | Other / unclassified | 125 ug | — |
| Comparator | Epinephrine | Other / unclassified | 200 ug | — |
| Comparator | Epinephrine | Other / unclassified | 300 ug | — |
| Comparator | Ketorolac | Other / unclassified | 30 mg | — |
Indications
No indication recorded.