drugset / Trial / NCT02242201

Total Hip Arthroplasty (THA) Lumbar Plexus Verses Periarticular

NCT02242201

Phase 4 Completed 165 enrolled Mayo Clinic
RandomizedParallel-groupSingle-blindTreatment

Summary

Total hip arthroplasty is a one of the most commonly performed surgical procedures with increasing numbers anticipated over the next several decades. The purpose of this study was to find a better way to make patients comfortable after their hip surgery. Three different ways of providing pain relief were compared, a peripheral nerve block in the lower back outside of the spinal space (using bupivacaine, a numbing medicine), or injections around the hip joint with one of two different medicines, either Ropivacaine or Liposomal Bupivacaine (Exparel®).

Timeline

Start
2014-09
Primary completion
2016-09
Completion
2016-09

Drugs

EvaluationDrugModalityDoseRoute
Comparator Bupivacaine Other / unclassified 0.2 %
Comparator Bupivacaine Other / unclassified 255 mg
Comparator Ropivacaine Other / unclassified 200 mg
Comparator Ropivacaine Other / unclassified 300 mg
Comparator Ropivacaine Other / unclassified 400 mg
Comparator Epinephrine Other / unclassified 100 ug
Comparator Epinephrine Other / unclassified 125 ug
Comparator Epinephrine Other / unclassified 200 ug
Comparator Epinephrine Other / unclassified 300 ug
Comparator Ketorolac Other / unclassified 30 mg

Indications

No indication recorded.