drugset / Trial / NCT02326727

Influence of Epidural Analgesia on Natural Killer Cell (NK) Activity After Colonic Cancer Surgery

NCT02326727

Unknown 30 enrolled Hillel Yaffe Medical Center
RandomizedSingle-groupSingle-blindTreatment

Summary

Regional anesthesia may decrease the release of endogenous opioids, increase Natural Killer cell (NK) function and decrease development of metastasis. The recent analysis of the Cancer Registry has noted an improved 5-year survival in patients who received epidural analgesia during surgery for colorectal carcinoma.

Timeline

Start
2015-04
Primary completion
2017-04
Completion
2017-05

Drugs

EvaluationDrugModalityDoseRoute
Comparator Ropivacaine Other / unclassified Other
Comparator Fentanyl Other / unclassified
Comparator Isoflurane Other / unclassified
Comparator Nitrous Oxide Other / unclassified
Comparator Propofol Small molecule

Indications