drugset / Trial / NCT02365727

Exparel vs Exparel Plus ACB in TKAs

NCT02365727

Phase 4 Withdrawn The Hawkins Foundation
RandomizedParallel-groupDouble-blindTreatment

Summary

Patients will be randomized (like the flip of a coin) to receive Exparel and a nerve block, standard of care for this procedure, or Exparel alone for pain management after surgery. They will also be asked to complete questionnaires before surgery, during their stay at the hospital after surgery, then at 3 months, 6 months and 12 months after surgery to assess pain and/or function levels, as well as the amount of pain medicine patients have used after surgery. Patients' leg strength will be measured immediately after surgery and again at 3, 6 and 12 months after surgery.

Timeline

Start
2015-04
Primary completion
2015-08
Completion
2015-08

Drugs

EvaluationDrugModalityDoseRoute
Subject Bupivacaine Other / unclassified
Subject Clonidine Other / unclassified 100 ug
Subject Epinephrine Other / unclassified
Subject Ropivacaine Other / unclassified 0.5 %

Indications