drugset / Trial / NCT02371759

Lidocaine + Clonidine for Intraoral Anesthesia in Patients With Diabetes Mellitus Type 2

NCT02371759

Phase 3 Completed 256 enrolled University of Belgrade
RandomizedParallel-groupQuadruple-blindSupportive care

Summary

The purpose of this study is to determine whether 2% lidocaine (L) + clonidine (C) (15 mcg/ml) as a vasoconstrictor achieves efficient (equal or better parameters of intraoral local anesthesia in comparison to 2% lidocaine + epinephrine (E) (1:80 000)) and safe (stable cardiovascular parameters - systolic, diastolic, mean blood pressure and heart rate) intraoral local anesthesia in patients with Diabetes mellitus type 2.

Timeline

Start
2013-06
Primary completion
2016-01
Completion
2016-01

Drugs

EvaluationDrugModalityDoseRoute
Subject Clonidine Other / unclassified 15 ug/ml Other
Comparator Epinephrine Other / unclassified Other
Background Lidocaine Other / unclassified 2 % Other

Indications