drugset / Trial / NCT02385539

Intrathecal Administration of Levobupivacaine and Opioids in Elderly

NCT02385539

Completed 240 enrolled Šarić, Jadranka Pavičić, M.D.
RandomizedParallel-groupDouble-blindTreatment

Summary

To find the optimal dose and combination of small dose of Levobupivacaine (LB) coadministered intrathecally with Fentanyl (F) or Sufentanil (S) with the highest probability for not developing hypotension and the lowest opioid side effect that would be sufficient to achieve and maintain a sensory block to the tenth thoracic dermatoma (T10) in elderly patients for surgery lasting \> 45 minutes as compared with large dose of Levobupivacaine alone.

Timeline

Start
2015-01
Primary completion
2015-09
Completion
2016-09

Drugs

EvaluationDrugModalityDoseRoute
Comparator Fentanyl Other / unclassified 25 ug Intrathecal
Comparator Fentanyl Other / unclassified 35 ug Intrathecal
Comparator Levobupivacaine Other / unclassified 6 mg Intrathecal
Comparator Levobupivacaine Other / unclassified 8 mg Intrathecal
Comparator Levobupivacaine Other / unclassified 12 mg Intrathecal
Comparator Sufentanil Other / unclassified 5 ug Intrathecal
Comparator Sufentanil Other / unclassified 7 ug Intrathecal

Indications

No indication recorded.