drugset / Trial / NCT02393482
Psychological Impact of Amenorrhea in Women With Endometriosis
RandomizedParallel-groupOpen-labelTreatment
Summary
The purpose of the study is to evaluate the impact on quality of life, psychological health, sexuality and chronic pain of therapies which determine amenorrhea in symptomatic women with endometriosis, through the administration of self reported questionnaires. Amenorrhea in the first group is caused by balanced assumption of estroprogestins, in the second group is caused by GnRHa-induced hypoestrogenism.
Timeline
- Start
- 2021-06
- Primary completion
- 2021-12
- Completion
- 2022-06
Publications
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Comparator | Leuprolide | Other / unclassified | 3.75 mg | Intramuscular |
| Comparator | Levonorgestrel | Small molecule | 20 ug | Oral |
| Comparator | etinilestradiol | Unknown | 100 ug | Oral |
| Comparator | Calcium carbonate | Other / unclassified | 500 mg | Oral |
| Comparator | Cholecalciferol | Other / unclassified | 400 iu | Oral |
| Comparator | Tibolone | Other / unclassified | 5 mg | Oral |