Adductor Canal Block and Recovery After Total Knee Replacement Surgery

Phase 4 Completed 200 enrolled University Health Network, Toronto

RandomizedParallel-groupDouble-blindTreatment

Summary

This study aims to compare the functional recovery of patients undergoing Total Knee Arthroplasty based on the administration of an adductor canal block during their anesthesia treatment

Timeline

Start: 2014-04
Primary completion: 2016-12
Completion: 2016-12

Publications

Background Puolakka PA, Rorarius MG, Roviola M, Puolakka TJ, Nordhausen K, Lindgren L. Persistent pain following knee arthroplasty. Eur J Anaesthesiol. 2010 May;27(5):455-60. doi: 10.1097/EJA.0b013e328335b31c.
Background Capdevila X, Barthelet Y, Biboulet P, Ryckwaert Y, Rubenovitch J, d'Athis F. Effects of perioperative analgesic technique on the surgical outcome and duration of rehabilitation after major knee surgery. Anesthesiology. 1999 Jul;91(1):8-15. doi: 10.1097/00000542-199907000-00006.
Background Busch CA, Shore BJ, Bhandari R, Ganapathy S, MacDonald SJ, Bourne RB, Rorabeck CH, McCalden RW. Efficacy of periarticular multimodal drug injection in total knee arthroplasty. A randomized trial. J Bone Joint Surg Am. 2006 May;88(5):959-63. doi: 10.2106/JBJS.E.00344.
Biswas A, Perlas A, Ghosh M, Chin K, Niazi A, Pandher B, Chan V. Relative Contributions of Adductor Canal Block and Intrathecal Morphine to Analgesia and Functional Recovery After Total Knee Arthroplasty: A Randomized Controlled Trial. Reg Anesth Pain Med. 2018 Feb;43(2):154-160. doi: 10.1097/AAP.0000000000000724.

Drugs

Evaluation	Drug	Modality	Dose	Route
Comparator	Morphine	Other / unclassified	100 ug	Other
Comparator	Ropivacaine	Other / unclassified	0.5 %	Other
Comparator	Ropivacaine	Other / unclassified	30 ml	Other
Comparator	Bupivacaine	Other / unclassified	0.5 %	Other
Comparator	Bupivacaine	Other / unclassified	3 ml	Other
Comparator	Epinephrine	Other / unclassified	—	Other

Indications

No indication recorded.