drugset / Trial / NCT02426164
Liposomal Bupivacaine in Total Knee Arthroplasty
Phase 4
Withdrawn
Miller Orthopedic Specialists
CHI Health Mercy Hospital · collabCreighton University Medical Center · collab
RandomizedParallel-groupDouble-blindTreatment
Summary
Liposomal bupivacaine is a novel local anesthetic designed for prolonged pain relief. Despite its long-acting analgesic potential, liposomal bupivacaine is significantly more expensive than other local anesthetic alternatives. The primary aim of this investigation is to examine whether or not liposomal bupivacaine provides superior pain relief or clinically significant opioid-sparing effects versus a control to justify its cost.
Timeline
- Start
- 2015-06
- Primary completion
- 2017-06
- Completion
- 2017-06
Outcome
Outcome not reported
Stopped: “Could not receive facility approval”
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Comparator | Bupivacaine | Other / unclassified | 20 ml | Other |
| Comparator | Epinephrine | Other / unclassified | 0.3 ml | Other |
| Comparator | Methylprednisolone | Other / unclassified | 1 ml | Other |
| Comparator | Morphine | Other / unclassified | 0.8 ml | Other |