Combined Intrathecal Morphine and Dexmedetomidine Analgesia

Phase 2/3 Completed 90 enrolled Assiut University

RandomizedParallel-groupQuadruple-blindTreatment

Summary

The current study investigated the effect of adding dexmedetomidine to intrathecal morphine for postoperative analgesia in cancer patients undergoing major abdominal surgery.

Timeline

Start: 2013-05
Primary completion: 2015-03
Completion: 2015-03

Publications

Abdel-Ghaffar HS, Mohamed SA, Fares KM. Combined Intrathecal Morphine and Dexmedetomidine for Postoperative Analgesia in Patients Undergoing Major Abdominal Cancer Surgery. Pain Med. 2016 Nov;17(11):2109-2118. doi: 10.1093/pm/pnw031. Epub 2016 Mar 21.

Drugs

Evaluation	Drug	Modality	Dose	Route
Comparator	Bupivacaine	Other / unclassified	10 mg	Intrathecal
Comparator	Dexmedetomidine	Other / unclassified	5 ug	Intrathecal
Comparator	Morphine	Other / unclassified	0.5 mg	Intrathecal

Indications

No indication recorded.