Perineural Steroids for Peripheral Nerve Blocks

Phase 4 Completed 85 enrolled Wake Forest University Health Sciences

RandomizedParallel-groupTriple-blindTreatment

This study will look at the efficacy of dexamethasone for prolongation of peripheral nerve blocks.

Met primary endpoint

paper Also, the 4 mg group was superior to the 1 mg group (p-value = 0.035), and the placebo group (29.7 ± 6.8 h, p-value = 0.011). PMID 29753264 ↗

Evaluation	Drug	Modality	Dose	Route
Subject	Dexamethasone	Small molecule	1 mg	Other
Subject	Dexamethasone	Small molecule	4 mg	Other
Background	Bupivacaine	Other / unclassified	20 ml	Other
Background	Epinephrine	Other / unclassified	—	Other