drugset / Trial / NCT02464176
Systemic Steroids for Peripheral Nerve Blocks
RandomizedParallel-groupTriple-blindTreatment
Summary
This study will investigate the ability of systemic dexamethasone to prolong the sensory block duration for lumbar plexus nerve blockade.
Timeline
- Start
- 2015-06
- Primary completion
- 2017-01
- Completion
- 2017-01
Outcome
Missed primary endpoint
paper However, neither group differed from placebo [19.6 h (6.7), (4 mg vs placebo), P=0.97; (8 mg vs placebo), P=0.77)]. PMID 29406180 ↗
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Dexamethasone | Small molecule | 4 mg | Intravenous |
| Subject | Dexamethasone | Small molecule | 8 mg | Intravenous |
| Background | Bupivacaine | Other / unclassified | 0.25 % | Other |
| Background | Epinephrine | Other / unclassified | — | Other |