drugset / Trial / NCT02627846
Laser Ablation Versus Mechanochemical Ablation Trial
RandomizedParallel-groupOpen-labelTreatment
Summary
A randomised clinical trial comparing endovenous laser ablation and mechanochemical ablation (ClariVein®) in the management of superficial venous insufficiency.
Timeline
- Start
- 2015-06-01
- Primary completion
- 2018-08-01
- Completion
- 2023-09-04
Publications
- Mohamed AH, Leung C, Wallace T, Smith G, Carradice D, Chetter I. A Randomized Controlled Trial of Endovenous Laser Ablation Versus Mechanochemical Ablation With ClariVein in the Management of Superficial Venous Incompetence (LAMA Trial). Ann Surg. 2021 Jun 1;273(6):e188-e195. doi: 10.1097/SLA.0000000000003749.
- Leung CC, Carradice D, Wallace T, Chetter IC. Endovenous laser ablation versus mechanochemical ablation with ClariVein((R)) in the management of superficial venous insufficiency (LAMA trial): study protocol for a randomised controlled trial. Trials. 2016 Aug 24;17(1):421. doi: 10.1186/s13063-016-1548-1.
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Comparator | Sodium Tetradecyl Sulfate | Unknown | 1.5 % | Intravenous |
| Comparator | Epinephrine | Other / unclassified | — | Subcutaneous |
| Comparator | Lidocaine | Other / unclassified | 1 % | Subcutaneous |
| Comparator | sodium bicarbonate | Diagnostic / imaging agent | 8.4 % | — |