drugset / Trial / NCT02739958
Effects of Propofol-dexmedetomidine on Immune Function in Patients With Cancer Larynx
RandomizedParallel-groupDouble-blindBasic science
Summary
The aim of this prospective, randomized clinical study is to compare between propofol and isoflurane on perioperative immune cell populations and function in patients undergoing total laryngectomy surgery.
Timeline
- Start
- 2016-03-01
- Primary completion
- 2016-08-30
- Completion
- 2016-10-30
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Comparator | Dexmedetomidine | Other / unclassified | 0.2 ug/kg | Intravenous |
| Comparator | Dexmedetomidine | Other / unclassified | 1 ug/kg | Intravenous |
| Comparator | Isoflurane | Other / unclassified | 2 % | — |
| Comparator | Isoflurane | Other / unclassified | 2.5 % | — |
| Comparator | Propofol | Small molecule | 1.5 mg/kg | Intravenous |
| Comparator | Propofol | Small molecule | 2 mg/kg | Intravenous |
| Comparator | Fentanyl | Other / unclassified | 50 ug | — |