Evaluate Use of Caudal Nerve Blocks in Adult Penile Prosthesis
Summary
During penile prosthesis surgery, patients are given general anesthesia in combination with other pain drugs. A caudal nerve block (CNB) is a local anesthetic injected near the tailbone, in addition to general anesthesia, which can lower the need for pain drugs. The goal of this clinical research study is to learn how effective CNBs are in patients who are having penile prosthesis surgery compared to patients who only have general anesthesia by studying how long you stay in the hospital and the level of pain you have after surgery. This is an investigational study. The general anesthesia and CNB used in this study are FDA approved and commercially available. It is considered investigational to compare the effectiveness of CNBs in penile prosthesis surgery to general anesthesia alone. The study doctor can explain how the study drugs are designed to work. Up to 104 participants will be enrolled in this study. All will take part at MD Anderson.
Timeline
- Start
- 2016-06
- Primary completion
- 2020-05-10
- Completion
- 2020-05-10
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Clonidine | Other / unclassified | 100 ug | Other |
| Subject | Dexamethasone | Small molecule | 10 mg | Other |
| Subject | Epinephrine | Other / unclassified | — | Other |
| Subject | Ropivacaine | Other / unclassified | 1 % | Other |
| Subject | Ropivacaine | Other / unclassified | 5 mg/kg | Other |
| Background | Propofol | Small molecule | — | — |