drugset / Trial / NCT02895035

Comparison of Epinephrine and Phenylephrine/Ketorolac With Regards to Pupil Size

NCT02895035

Phase 4 Terminated 59 enrolled Milton S. Hershey Medical Center
RandomizedCrossoverDouble-blindOther

Summary

The objective of this study is to compare the maintenance of intraoperative mydriasis during cataract surgery between two drugs: epinephrine, which has routinely been used for decades, and Omidria, a newly FDA approved combination drug of phenylephrine and ketorolac. Patients undergoing cataract surgery that are enrolled in the trial will randomly receive one of the drugs in one eye, and the other eye will receive the drug during the subsequent cataract surgery.

Timeline

Start
2016-09-01
Primary completion
2018-12-31
Completion
2018-12-31

Drugs

EvaluationDrugModalityDoseRoute
Comparator Epinephrine Other / unclassified Other
Comparator Ketorolac Other / unclassified 3 % Other
Comparator Phenylephrine Small molecule 1 % Other

Indications