drugset / Trial / NCT02909140

Optimal Method for Mydriasis in Cataract Surgery

NCT02909140

Terminated 3 enrolled Johns Hopkins University
RandomizedParallel-groupOpen-labelOther

Summary

Obtaining appropriate mydriasis prior to cataract surgery is an important variable in successful surgery. The current practice includes using topical anticholinergic and sympathomimetic agents in the preoperative area prior to cataract surgery, but the pupils are sometimes insufficiently dilated and can often need additional mydriasis with intracameral agents during cataract surgery. Pre-operative topical mydriatic drops take time to take effect, are mildly uncomfortable for the patient, and have a cost to the healthcare system. If intracameral mydriasis alone can achieve adequate pupil dilation, perhaps topical mydriatics would not be needed. The purpose of this study is to evaluate whether topical versus intracameral versus topical + intracameral mydriasis is the optimal way to dilate pupils during routine cataract surgery. The results of this study have implications for improving the efficiency and reducing time prior to cataract surgery. In addition, it has significant potential to reduce the cost associated with cataract surgery if preoperative drops can be eliminated.

Timeline

Start
2016-09
Primary completion
2018-08-15
Completion
2018-08-15

Drugs

EvaluationDrugModalityDoseRoute
Subject Epinephrine Other / unclassified 0.2 ml Other
Subject Epinephrine Other / unclassified 0.3 ml Other
Subject Phenylephrine Small molecule 2.5 % Topical
Subject cyclopentolate Unknown 1 % Topical
Background Lidocaine Other / unclassified 1 % Other

Indications