drugset / Trial / NCT02938442

Vaccination of Triple Negative Breast Cancer Patients

NCT02938442

Phase 1/2 Completed 16 enrolled University of Arkansas
RandomizedParallel-groupOpen-labelTreatment

Summary

The purpose of this study is to evaluate a new investigational cancer vaccine, P10s-PADRE in combination with standard neoadjuvant chemotherapy and surgery in patients with clinical stage I, II or III triple negative breast cancer (TNBC). This study will compare the vaccine plus standard neoadjuvant chemotherapy and surgery to standard neoadjuvant chemotherapy and surgery alone.

Timeline

Start
2019-01-25
Primary completion
2023-01-09
Completion
2023-01-09

Drugs

EvaluationDrugModalityDoseRoute
Subject P10s-PADRE Peptide
Background Cyclophosphamide Other / unclassified
Background Doxorubicin Other / unclassified
Background Paclitaxel Small molecule
Background incomplete Freund's adjuvant Other / unclassified