drugset / Trial / NCT02944825
Antibiotic Prophylaxis With Routine Ureteral Stent Removal
RandomizedParallel-groupSingle-blindPrevention
Summary
This study will be a single-institutional randomized, single-blinded prospectively controlled clinical trial of a single dose of Ciprofloxicin 500mg antibiotic tablet as prophylaxis at the time of office flexible cystoscopy with ureteral stent removal. The control group will be no prophylaxis oral antibiotics.
Timeline
- Start
- 2016-01
- Primary completion
- 2025-01
- Completion
- 2025-03
Publications
- Background National Nosocomial Infections Surveillance (NNIS) report, data summary from October 1986-April 1996, issued May 1996. A report from the National Nosocomial Infections Surveillance (NNIS) System. Am J Infect Control. 1996 Oct;24(5):380-8. No abstract available.
- Background Urban JA. Cost analysis of surgical site infections. Surg Infect (Larchmt). 2006;7 Suppl 1:S19-22. doi: 10.1089/sur.2006.7.s1-19.
- Background Wolf JS Jr, Bennett CJ, Dmochowski RR, Hollenbeck BK, Pearle MS, Schaeffer AJ; Urologic Surgery Antimicrobial Prophylaxis Best Practice Policy Panel. Best practice policy statement on urologic surgery antimicrobial prophylaxis. J Urol. 2008 Apr;179(4):1379-90. doi: 10.1016/j.juro.2008.01.068. Epub 2008 Feb 20.
- Background Ramaswamy K, Shah O. Antibiotic prophylaxis after uncomplicated ureteroscopic stone treatment: is there a difference? J Endourol. 2012 Feb;26(2):122-5. doi: 10.1089/end.2011.0360. Epub 2011 Oct 17.
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Comparator | Ciprofloxacin | Small molecule | 500 mg | Oral |
| Comparator | Sulfamethoxazole | Small molecule | 800 mg | Oral |
| Comparator | Trimethoprim | Small molecule | 160 mg | Oral |