drugset / Trial / NCT03005496
The Effect of Zinc, β-carotene, and Vitamin D3 in Preterm Delivery Through Placental MyD88, TRIF, NFkB, and IL-1β
Non-randomizedParallel-groupOpen-labelBasic science
Summary
This study is a controlled trial which compares the effect of zinc, beta-carotene, and Vitamin D3 supplementation in pregnant women which has preterm birth. The measured outcome is zinc, vitamin A, and 25(OH)D level in serum and placenta, MyD88, TRIF, NFκB, and IL-1β levels in placenta.
Timeline
- Start
- 2017-01
- Primary completion
- 2017-04
- Completion
- 2017-06
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Comparator | Cholecalciferol | Other / unclassified | 50000 iu | Oral |
| Comparator | Zinc Sulfate | Unknown | 50 mg | Oral |
| Comparator | beta-carotene | Small molecule | 25000 iu | Oral |
| Comparator | Dexamethasone | Small molecule | 6 mg | Intravenous |
| Comparator | Nifedipine | Other / unclassified | 10 mg | Oral |
Indications
No indication recorded.