Prospective Evaluation of Topical Analgesia for Laceration Repair in the Emergency Department

Phase 4 Completed 132 enrolled Centre Hospitalier le Mans University Hospital, Angers · collab

RandomizedParallel-groupOpen-labelTreatment

Summary

The purpose of this study is to determine if topical analgesia using a lidocaine and prilocaine cream improves pain scores compared to the usual local anesthesia using subcutaneous 1% lidocaine and adrenalin injected near the laceration.

Timeline

Start: 2017-12-01
Primary completion: 2021-12-31
Completion: 2021-12-31

Publications

Results McNulty RJ, Handley TP, Devlin MF. Reducing the need for general anaesthesia in children: use of LAT gel in treating facial lacerations. Br J Oral Maxillofac Surg. 2013 Sep;51(6):e130-1. doi: 10.1016/j.bjoms.2012.04.259. Epub 2012 Jun 12.
Results White NJ, Kim MK, Brousseau DC, Bergholte J, Hennes H. The anesthetic effectiveness of lidocaine-adrenaline-tetracaine gel on finger lacerations. Pediatr Emerg Care. 2004 Dec;20(12):812-5. doi: 10.1097/01.pec.0000148029.61222.9f.

Drugs

Evaluation	Drug	Modality	Dose	Route
Subject	Epinephrine	Other / unclassified	0.005 mg/ml	Subcutaneous
Subject	Lidocaine	Other / unclassified	1 %	Topical
Subject	Lidocaine	Other / unclassified	2.5 %	Topical
Subject	prilocaine	Small molecule	2.5 %	Topical

Indications

No indication recorded.