drugset / Trial / NCT03261921

Caudal Combination of Dexamethasone and/or Dexmedetomidine to Bupivacaine in Pediatric Hypospadias Surgery

NCT03261921

Phase 1 Completed 63 enrolled Cairo University
RandomizedFactorialTriple-blindDiagnostic

Summary

One of the most commonly used regional anesthetic techniques in pediatric surgeries is the caudal epidural block. Its main disadvantage remains the short duration of action. Hence, different additives have been used. Dexmedetomidine as an additive to the local anesthetic bupivacaine in caudal epidural analgesia prolongs the duration of postoperative analgesia so is dexamethasone. The investigators aimed to study the effect of combining both additives in the duration of analgesia, decreasing side effects and decreasing anesthetic doses

Timeline

Start
2016-06-05
Primary completion
2017-06-22
Completion
2017-07-07

Drugs

EvaluationDrugModalityDoseRoute
Comparator Dexamethasone Small molecule 0.1 mg/kg Other
Comparator Dexmedetomidine Other / unclassified 0.01 ug/kg Other
Comparator Bupivacaine Other / unclassified 0.25 % Other

Indications

No indication recorded.