drugset / Trial / NCT03261921
Caudal Combination of Dexamethasone and/or Dexmedetomidine to Bupivacaine in Pediatric Hypospadias Surgery
RandomizedFactorialTriple-blindDiagnostic
Summary
One of the most commonly used regional anesthetic techniques in pediatric surgeries is the caudal epidural block. Its main disadvantage remains the short duration of action. Hence, different additives have been used. Dexmedetomidine as an additive to the local anesthetic bupivacaine in caudal epidural analgesia prolongs the duration of postoperative analgesia so is dexamethasone. The investigators aimed to study the effect of combining both additives in the duration of analgesia, decreasing side effects and decreasing anesthetic doses
Timeline
- Start
- 2016-06-05
- Primary completion
- 2017-06-22
- Completion
- 2017-07-07
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Comparator | Dexamethasone | Small molecule | 0.1 mg/kg | Other |
| Comparator | Dexmedetomidine | Other / unclassified | 0.01 ug/kg | Other |
| Comparator | Bupivacaine | Other / unclassified | 0.25 % | Other |
Indications
No indication recorded.