drugset / Trial / NCT03296137
Adoptive Cell Therapy Across Cancer Diagnoses
NaSingle-groupOpen-labelTreatment
Summary
This study will perform tumor-infiltrating lymphocyte (TIL)-based adoptive T-cell therapy in combination with checkpoint inhibition on cancer patients across all cancer diagnoses.
Timeline
- Start
- 2017-10-13
- Primary completion
- 2020-03-13
- Completion
- 2020-07-01
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Autologous Tumor Infiltrating Lymphocytes | Cell therapy | — | Intravenous |
| Subject | Ipilimumab | Monoclonal antibody | 3 mg/kg | — |
| Subject | Nivolumab | Monoclonal antibody | 3 mg/kg | — |
| Background | Cyclophosphamide | Other / unclassified | 60 mg/kg | — |
| Background | Fludarabine | Small molecule | 25 mg/m2 | — |
| Background | aldesleukin | Protein / enzyme biologic | 2 iu | Subcutaneous |