drugset / Trial / NCT03296137

Adoptive Cell Therapy Across Cancer Diagnoses

NCT03296137

Phase 1/2 Completed 25 enrolled Inge Marie Svane
NaSingle-groupOpen-labelTreatment

Summary

This study will perform tumor-infiltrating lymphocyte (TIL)-based adoptive T-cell therapy in combination with checkpoint inhibition on cancer patients across all cancer diagnoses.

Timeline

Start
2017-10-13
Primary completion
2020-03-13
Completion
2020-07-01

Drugs

EvaluationDrugModalityDoseRoute
Subject Autologous Tumor Infiltrating Lymphocytes Cell therapy Intravenous
Subject Ipilimumab Monoclonal antibody 3 mg/kg
Subject Nivolumab Monoclonal antibody 3 mg/kg
Background Cyclophosphamide Other / unclassified 60 mg/kg
Background Fludarabine Small molecule 25 mg/m2
Background aldesleukin Protein / enzyme biologic 2 iu Subcutaneous

Indications