Different Peribulbar Blocks With SPI-guided Anaesthesia for VRS (P&MSPIVRS)

Completed 184 enrolled Medical University of Silesia Silesian University of Medicine · collab

RandomizedParallel-groupTriple-blindPrevention

Summary

The aim of this randomized trial is to assess the efficacy of preventive analgesia using different peribulbar blocks (PBB) under SPI-guided anaesthesia for vitreoretinal surgery (VRS), presence of PONV (postoperative nausea and vomiting) and oculocardiac reflex (OCR) and compare Numerical Rating Scale (NRS) with Surgical Pleth Index (SPI) for monitoring pain perception postoperatively. Patients will receive general anaesthesia combined with either preventive PBB using either lidocaine with bupivacaine or bupivacaine or ropivacaine

Timeline

Start: 2018-04-26
Primary completion: 2022-12-20
Completion: 2022-12-20

Publications

Drugs

Evaluation	Drug	Modality	Dose	Route
Subject	Acetaminophen	Small molecule	10 mg/kg	Intravenous
Subject	Acetaminophen	Small molecule	15 mg/kg	Intravenous
Subject	Bupivacaine	Other / unclassified	0.5 %	Other
Subject	Bupivacaine	Other / unclassified	2.5 ml	Other
Subject	Bupivacaine	Other / unclassified	5 ml	Other
Subject	Lidocaine	Other / unclassified	2 %	Other
Subject	Lidocaine	Other / unclassified	2.5 ml	Other
Subject	Ropivacaine	Other / unclassified	0.75 %	Other
Subject	Ropivacaine	Other / unclassified	1 %	Other
Subject	Ropivacaine	Other / unclassified	5 ml	Other

Indications

No indication recorded.