drugset / Trial / NCT03498092

Dexmedetomidine in Serratus Plane Block for Mastectomy

NCT03498092 ↗

Completed 150 enrolled Alaa Mazy
RandomizedParallel-groupQuadruple-blindSupportive care

Summary

The serratus plane block (SPB) described by Blanco et al, 2013 is a progression from the work with the Pecs I and II blocks. The serratus muscle is a superficial and easily identified muscle and considered a true landmark to perform thoracic wall blocks because lateral cutaneous branches of the intercostal nerves pierce it in the mid-axillary line. A local anesthetic (LA) is injected under ultrasound (US) guidance either superficial or deep to serratus anterior muscle providing predictable and relatively long-lasting regional anesthesia, which would be suitable for surgical procedures performed on the chest wall. The linear US probe of frequency (6-13 MHz) is placed over the mid-clavicular region in a sagittal plane.The ribs are counted inferiorly and laterally until the fifth rib in the midaxillary line is identified.The latissimus dorsi, teres major, and serratus muscles are identified.

Timeline

Start
2016-08-08
Primary completion
2018-10-08
Completion
2018-10-08

Drugs

EvaluationDrugModalityDoseRoute
Comparator Bupivacaine Other / unclassified 2.5 mg/ml Other
Subject Dexmedetomidine Other / unclassified 1 ug/kg Other
Background Epinephrine Other / unclassified 5 ug/ml Other

Indications

No indication recorded.