drugset / Trial / NCT03599089
Study of CA-008 (Vocacapsaicin) in Bunionectomy Patients
RandomizedParallel-groupQuadruple-blindTreatment
Summary
This is a Phase 2, multi-center, randomized, double-blind, placebo-controlled, parallel design study evaluating a single dose of one of three CA-008 dose levels vs. placebo injected during an elective bunionectomy Bunionectomy to assess post-surgical pain management and the need for rescue medication (oxycodone).
Timeline
- Start
- 2018-07-09
- Primary completion
- 2018-10-10
- Completion
- 2018-10-23
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Comparator | vocacapsaicin | Small molecule | 0.7 mg | Other |
| Comparator | vocacapsaicin | Small molecule | 2.1 mg | Other |
| Comparator | vocacapsaicin | Small molecule | 4.2 mg | Other |
| Comparator | Acetaminophen | Small molecule | 1000 mg | Intravenous |
| Comparator | Bupivacaine | Other / unclassified | 0.5 % | Other |
| Comparator | Ketorolac | Other / unclassified | 30 mg | Intravenous |
| Comparator | Oxycodone | Other / unclassified | 5 mg | Oral |