drugset / Trial / NCT03791801
The Use of Sugammadex in the Critically Ill
Unknown
50 enrolled
McGill University Health Centre/Research Institute of the McGill University Health Centre
RandomizedParallel-groupDouble-blindSupportive care
Summary
Moderate and Deep neuromuscular blockade (rocuronium administered to a train of four count 0 and post-tetanic count of 1-2) in critically ill patients needing intubation or procedures can be reversed immediately and effectively by sugammadex avoiding unnecessary paralysis in an already weakened population
Timeline
- Start
- 2019-09-01
- Primary completion
- 2020-12-01
- Completion
- 2021-07-01
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Comparator | Neostigmine | Other / unclassified | 5 ug/kg | — |
| Comparator | Neostigmine | Other / unclassified | 70 ug/kg | — |
| Comparator | Rocuronium | Other / unclassified | 1 mg/kg | — |
| Comparator | Sugammadex | Other / unclassified | 4 mg/kg | — |
| Comparator | Glycopyrrolate | Small molecule | 10 ug/kg | — |
Indications
No indication recorded.