drugset / Trial / NCT03910088
Pregabalin Versus Hydrocortisone for Postdural Puncture Headache After Spinal for Cesarean
RandomizedParallel-groupSingle-blindTreatment
Summary
Postdural puncture headache (PDPH) is a common complication after spinal anesthesia. The role of pregabalin and hydrocortisone in the treatment of PDPH is unclear. The aim of this work is to assess and compare the efficacy of both drugs in severe cases of PDPH after spinal anesthesia for elective cesarean section.
Timeline
- Start
- 2019-04-20
- Primary completion
- 2019-06-30
- Completion
- 2019-06-30
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Comparator | Hydrocortisone | Other / unclassified | 100 mg | Intravenous |
| Comparator | Pregabalin | Small molecule | 100 mg | Oral |
| Comparator | Acetaminophen | Small molecule | 500 mg | Oral |
| Comparator | Caffeine | Small molecule | 65 mg | Oral |
| Comparator | Diclofenac | Other / unclassified | 50 mg | Oral |