drugset / Trial / NCT04025593

Biomarker Guided Treatment in DLBCL

NCT04025593 ↗

Phase 2 Unknown 128 enrolled Ruijin Hospital
RandomizedParallel-groupOpen-labelTreatment

Summary

This study is to investigate the strategy of biomarker guided treatment in diffuse large B cell lymphoma

Timeline

Start
2019-07-17
Primary completion
2021-07-01
Completion
2023-06-01

Drugs

EvaluationDrugModalityDoseRoute
Subject Decitabine Small molecule 10 mg/m2 —
Subject Ibrutinib Small molecule 420 mg —
Subject Lenalidomide Other / unclassified 25 mg —
Subject Tucidinostat Small molecule 20 mg —
Background Cyclophosphamide Other / unclassified 750 mg/m2 —
Background Doxorubicin Other / unclassified 50 mg/m2 —
Background Prednisone Other / unclassified 60 mg/m2 —
Background Rituximab Monoclonal antibody 375 mg/m2 —
Background Vincristine Small molecule 1.4 mg/m2 —