drugset / Trial / NCT04063046

Effect of Anesthesia Technique on Early Outcome in Diabetic Patients Undergoing Lower Extremity Amputation

NCT04063046

Unknown 158 enrolled Yonsei University
RandomizedParallel-groupSingle-blindTreatment

Summary

The aim of this study was to compare 1. early prognosis (mortality, morbidity) 2. changes in concentrations of serum syndecan-1,partial pressure of oxygen(on arterial blood gas analysis), perioperative transfusion, intraoperative vasopressor use between general anesthesia and nerve block in diabetic patients undergoing limb amputation surgery as a prospective randomized trial.

Timeline

Start
2019-11-12
Primary completion
2021-07
Completion
2021-09

Drugs

EvaluationDrugModalityDoseRoute
Comparator Propofol Small molecule 0.5 mg/kg
Comparator Propofol Small molecule 2 mg/kg
Comparator Remifentanil Small molecule 4 ug/kg
Comparator Remifentanil Small molecule 8 ug/kg
Comparator Rocuronium Other / unclassified 0.4 mg/kg
Comparator Rocuronium Other / unclassified 0.6 mg/kg
Comparator Sevoflurane Other / unclassified 1 %
Comparator Sevoflurane Other / unclassified 2.5 %

Indications

No indication recorded.