drugset / Trial / NCT04189640

Ultrasound-Guided Adductor Canal Block for Total Knee Arthroplasty Surgery

NCT04189640

Withdrawn Medipol University
RandomizedParallel-groupTriple-blindTreatment

Summary

The ultrasound-guided selective blockade of the saphenous nerve in the adductor canal provides effective analgesia and reduces postoperative pain in patients undergoing arthroscopic medial meniscectomy. Selective blockade of the saphenous nerve in the adductor canal provides effective analgesia without quadriceps muscle weakness. It has been shown that the adductor canal block (ACB) block increases the spread of local anesthetics in a distal and proximal way. Therefore, the proximal spread of local anesthetics may cause possible quadriceps weakness. The distal spread of local anesthetics may increase analgesic effect via sciatic nerve. The different volumes for ACB is a topic of discussion. The aim of this study is to compare the different volumes of US-guided ACB performing for postoperative analgesia management after total knee arthroplasty surgery.

Timeline

Start
2020-01-10
Primary completion
2022-06-30
Completion
2022-06-30

Drugs

EvaluationDrugModalityDoseRoute
Comparator Bupivacaine Other / unclassified 20 ml
Comparator Bupivacaine Other / unclassified 30 ml
Comparator Bupivacaine Other / unclassified 40 ml
Comparator Fentanyl Other / unclassified 10 ug/ml
Comparator Ibuprofen Small molecule 400 mg Intravenous
Comparator Tramadol Other / unclassified 0.5 mg/kg Intravenous