drugset / Trial / NCT04310748
Effects of TIVA and Inhalation Anesthesia on Oxidative Stress Factors During Hypotensive Anesthesia
RandomizedParallel-groupSingle-blindScreening
Summary
Total intravenous anesthesia (TIVA) and inhalation anesthesia are two anesthesia methods that can be preferred for the maintenance of anesthesia. Sevoflurane and propofol are drugs used frequently in these methods. This study aims to investigate and compare the effects of inhalation anesthesia using sevoflurane and TIVA using propofol on oxidative stress in patients undergoing controlled hypotensive anesthesia.
Timeline
- Start
- 2020-05-01
- Primary completion
- 2020-10-01
- Completion
- 2021-01-10
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Comparator | Nitrous Oxide | Other / unclassified | — | Inhaled |
| Comparator | Propofol | Small molecule | 6 mg/kg | Intravenous |
| Comparator | Propofol | Small molecule | 10 mg/kg | Intravenous |
| Comparator | Remifentanil | Small molecule | 0.3 ug/kg | — |
| Comparator | Remifentanil | Small molecule | 0.4 ug/kg | — |
| Comparator | Sevoflurane | Other / unclassified | 2 % | Inhaled |
| Comparator | Sevoflurane | Other / unclassified | 3 % | Inhaled |
Indications
No indication recorded.