drugset / Trial / NCT04355468
Opioid Free Anesthesia in Thoracic Surgery
RandomizedSingle-groupSingle-blindTreatment
Summary
Proper assessment of pain and adequate analgesia in thoracic surgery is a challenging issue for medical practitioners. Basic aspects of thoracic anaesthesia are general anesthesia, intubation with double lumen tube and separation of lung ventilation, however proper analgesia needs to be standardized. Role of opioids in this clinical setting is reduced due to high risk of respiratory system complications. Instead, use of opioid free anaesthesia and regional anaesthesia is proposed. The aim of this study is to compare the use of opioid anaesthesia with opioid free anaesthesia and paravertebral block.
Timeline
- Start
- 2015-12
- Primary completion
- 2018-03
- Completion
- 2018-03
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Bupivacaine | Other / unclassified | 0.5 % | Other |
| Comparator | Fentanyl | Other / unclassified | 1 ug/kg | — |
| Comparator | Fentanyl | Other / unclassified | 3 ug/kg | — |
| Subject | Ketamine | Small molecule | 0.12 mg/kg | Intravenous |
| Subject | Lidocaine | Other / unclassified | 1.2 mg/kg | Intravenous |
Indications
No indication recorded.