Post-cesarean Analgesia With Epidural Morphine Following Epidural 2-chloroprocaine

Phase 4 Completed 44 enrolled The University of Texas Health Science Center, Houston

RandomizedParallel-groupSingle-blindTreatment

Summary

The purpose of this study is to show that the effect of 3% 2-chloroprocaine prior to epidural morphine administration will be not inferior to the effect of epidural 2% lidocaine with 1:200,000 epinephrine on total opioid use for 24h

Timeline

Start: 2020-05-11
Primary completion: 2021-05-11
Completion: 2021-07-11

Publications

Lee LO, Ramirez-Chapman AL, White DL, Zhang X, Lu M, Suresh MS. Postcesarean Analgesia With Epidural Morphine After Epidural 2-Chloroprocaine: A Randomized Noninferiority Trial. Anesth Analg. 2023 Jan 1;136(1):86-93. doi: 10.1213/ANE.0000000000006109. Epub 2022 Jun 3.

Drugs

Evaluation	Drug	Modality	Dose	Route
Subject	Chloroprocaine	Other / unclassified	3 %	Other
Comparator	Lidocaine	Other / unclassified	2 %	Other
Comparator	Morphine	Other / unclassified	3 mg	Other
Comparator	Epinephrine	Other / unclassified	—	Other

Indications

No indication recorded.