Oral Anti Diabetic Agents in the Hospital
Summary
This randomized controlled clinical trial will assess whether continuation of home oral antidiabetic agents during hospitalization can be used as a safe and effective alternative to insulin therapy in the management of diabetes in the hospital. The primary outcome of the study is to determine differences in glycemic control as measured by mean daily blood glucose (BG) concentration between oral antidiabetic medications and basal bolus therapy in hospitalized patients with type 2 diabetes (T2D).
Timeline
- Start
- 2020-08-07
- Primary completion
- 2025-04-11
- Completion
- 2025-04-11
Outcome
Outcome not reported
Stopped (Enrollment): “The study was suspended and during this time recruitment and study activities were halted. The study was ultimately terminated in April 2026 without having re-opened for recruitment additional participants.”
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Metformin | Small molecule | — | — |
| Subject | Pioglitazone | Small molecule | — | — |
| Comparator | insulin detemir | Protein / enzyme biologic | — | — |
| Comparator | insulin glargine | Protein / enzyme biologic | — | — |
| Background | Insulin Lispro | Protein / enzyme biologic | — | — |
| Background | insulin aspart | Protein / enzyme biologic | — | — |