drugset / Trial / NCT04606264

Recommendations of Enhanced Recovery Interventions for Patient's Clinical Team and Collection of Associated Data

NCT04606264

Phase 3 Completed 3395 enrolled Jennifer Holder-Murray Berry Consultants · collab
RandomizedSequentialOpen-labelTreatment

Summary

This REMAP Periop ERP domain study falls under the Periop Core Protocol, which compares the different recommended strategies for enhancing recovery through the use of various standard of care treatments before, during and after surgery in all patients with elective surgical encounters at UPMC who meet eligibility criteria. The ERP domain seeks to enhance recovery by optimizing strategies of perioperative care through evaluating combinations of perioperative treatment, which consists of preoperative, intraoperative and postoperative care. Optimal combinations of perioperative care will be generated and analyzed to determine the best outcomes for patients as defined by reduction in hospital free days, reduction in postoperative nausea and vomiting, and improved pain control.

Timeline

Start
2023-05-15
Primary completion
2025-03-21
Completion
2025-03-21

Drugs

EvaluationDrugModalityDoseRoute
Comparator Aprepitant Other / unclassified 40 mg Oral
Comparator Dexamethasone Small molecule Intravenous
Comparator Dimenhydrinate Small molecule 25 mg Oral
Comparator Ondansetron Other / unclassified 4 mg Oral
Comparator Perphenazine Small molecule 8 mg Oral

Indications

No indication recorded.