Minimum Effective Volume for Selective Trunk Block

Completed 25 enrolled Chinese University of Hong Kong

NaSingle-groupOpen-labelTreatment

Summary

The objective of this study is to identify the minimum effective dosage of a mixture of two local anaesthetic drugs called 'levobupivacaine' and 'lignocaine with epinephrine" used to produce an effective ultrasound guided selective trunk block for surgical anaesthesia of the upper limb.

Timeline

Start: 2021-03-10
Primary completion: 2021-11-12
Completion: 2021-11-17

Publications

Sivakumar RK, Karmakar MK, Wong RSL, Samy W. Minimum effective volume 90% for ultrasound-guided selective trunk block: A quantal bioassay. Eur J Anaesthesiol. 2025 Sep 1;42(9):800-807. doi: 10.1097/EJA.0000000000002160. Epub 2025 Mar 11.

Drugs

Evaluation	Drug	Modality	Dose	Route
Subject	Epinephrine	Other / unclassified	5 ug/ml	Other
Subject	Levobupivacaine	Other / unclassified	0.5 %	Other
Subject	Lidocaine	Other / unclassified	2 %	Other

Minimum Effective Volume for Selective Trunk Block

Summary

Timeline

Publications

Drugs

Indications