drugset / Trial / NCT04790292

Impact of Dexamethasone Added to Intra-articular Morphine and Bupivacaine for Post-operative Analgesia After Knee Arthroscopy

NCT04790292 ↗

Phase 4 Completed 40 enrolled Ain Shams University
RandomizedParallel-groupQuadruple-blindTreatment

Summary

A randomized double-blinded clinical trial was carried out on 40 patients undergoing knee arthroscopy. Patients were divided randomly into two equal groups. All drugs used were injected intra-articularly at the end of arthroscopy. In the control group, patients were administered 10mg morphine added to bupivacaine 25mg. In the study group, patients were administered 10mg morphine and 8mg dexamethasone added to bupivacaine 25mg. Visual analog score for pain at rest and movement, time to first analgesic request, total analgesic consumption, duration of analgesia and adverse effects were recorded.

Timeline

Start
2020-01-01
Primary completion
2020-07-01
Completion
2020-08-01

Drugs

EvaluationDrugModalityDoseRoute
Subject Dexamethasone Small molecule 8 mg Other
Background Bupivacaine Other / unclassified 0.25 % Other
Background Morphine Other / unclassified 10 mg Other

Indications

No indication recorded.