drugset / Trial / NCT04814433

Evaluating Postoperative Non-Opioid Pain Management Utilizing Local Anesthetics Coupled With Modulated Coagulation

NCT04814433

Phase 4 Terminated 46 enrolled NYU Langone Health
RandomizedParallel-groupSingle-blindTreatment

Summary

This study is a prospective randomized trial examining the effect of topically combined antifibrinolytics (Tranexamic acid) with local anesthetics in all electively created surgical wound beds in hand surgery to provide long term pain relief and decrease the use of postoperative narcotics.

Timeline

Start
2021-03-24
Primary completion
2023-07-10
Completion
2023-07-10

Drugs

EvaluationDrugModalityDoseRoute
Subject Aminocaproic Acid Small molecule 1000 mg Topical
Subject Tranexamic Acid Small molecule 500 mg Topical
Subject thrombin Protein / enzyme biologic 10000 iu Topical
Background Bupivacaine Other / unclassified 5 ml Topical
Background Lidocaine Other / unclassified 5 ml Topical

Indications

No indication recorded.