drugset / Trial / NCT05186454

Postoperative Pain Control by Use of Many Drugs in Small Doses Intrathecally

NCT05186454

Phase 2 Unknown 60 enrolled Sohag University
RandomizedParallel-groupQuadruple-blindHealth-services research

Summary

Cesarean section is one of the painful operations that require adequate postoperative analgesia. Patients are divided into two groups: Multimodal (DMM) group ( 30 patients): patients will receive spinal anesthesia with 10-12.5 mg bupivacaine and 1 ml containing 2 mg dexamethasone, 50 µg morphine, and 500 µg midazolam. Morphine (M) group (30 patients): patients will receive spinal anesthesia with 10-12.5 mg bupivacaine and 1 ml containing 200 µg morphine

Timeline

Start
2021-05-23
Primary completion
2022-02-10
Completion
2022-02-15

Drugs

EvaluationDrugModalityDoseRoute
Comparator Dexamethasone Small molecule 2 mg Intrathecal
Comparator Midazolam Small molecule 500 ug Intrathecal
Comparator Morphine Other / unclassified 50 ug Intrathecal
Comparator Morphine Other / unclassified 200 ug Intrathecal
Comparator Bupivacaine Other / unclassified Intrathecal

Indications

No indication recorded.