drugset / Trial / NCT05303311
Intrathecal Pethidine Plus Dexamethasone for Distal Lower Orthopedic Surgeries
RandomizedParallel-groupDouble-blindTreatment
Summary
Bupivacaine is commonly used as a sole agent for spinal anesthesia unlike pethidine. Pethidine (meperidine) is a unique opioid. In addition to its analgesic activity, it also has significant local anesthetic activity. This property enables it to be used as the sole agent for spinal anesthesia
Timeline
- Start
- 2022-01-15
- Primary completion
- 2024-01-15
- Completion
- 2024-03-15
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Comparator | Bupivacaine | Other / unclassified | 0.5 % | Intrathecal |
| Comparator | Bupivacaine | Other / unclassified | 3 ml | Intrathecal |
| Comparator | Dexamethasone | Small molecule | 4 mg | Intrathecal |
| Comparator | Meperidine | Unknown | 1 mg/kg | Intrathecal |
Indications
No indication recorded.