Quick Epidural Top-up With Alkalinized Lidocaine for Emergent Caesarean Delivery

Phase 2/3 Completed 65 enrolled University Hospital, Bordeaux

RandomizedParallel-groupSingle-blindTreatment

Summary

Prospective randomized study comparing the use of lidocaine 2% with epinephrine buffered with sodium bicarbonate and lidocaine 2% with epinephrine as epidural top-up for extremely urgent cesarean section during labour.

Timeline

Start: 2022-07-14
Primary completion: 2024-07-08
Completion: 2024-07-08

Publications

Lechat T, d'Aprigny T, Henriot J, Arthur J, Sylla D, Benard A, Nouette-Gaulain K. Quick Epidural Top-up with Alkalinized Lidocaine for emergent caesarean delivery (QETAL study): protocol for a randomized, controlled, bicentric trial. Trials. 2023 May 19;24(1):341. doi: 10.1186/s13063-023-07366-1.

Drugs

Evaluation	Drug	Modality	Dose	Route
Comparator	Lidocaine	Other / unclassified	2 %	Other
Comparator	Lidocaine	Other / unclassified	10 ml	Other
Comparator	Lidocaine	Other / unclassified	20 ml	Other
Subject	sodium bicarbonate	Diagnostic / imaging agent	2 ml	Other
Subject	sodium bicarbonate	Diagnostic / imaging agent	4.2 %	Other
Comparator	Epinephrine	Other / unclassified	—	Other

Quick Epidural Top-up With Alkalinized Lidocaine for Emergent Caesarean Delivery

Summary

Timeline

Publications

Drugs

Indications