drugset
drugset / Trial / NCT05809180

Pro-miniCHOP-like Regimen for Treatment-naive Elderly Patients

NCT05809180 ↗

Unknown 35 enrolled The First Affiliated Hospital of Soochow University
NaSingle-groupOpen-labelTreatment

Summary

The proposed study is a prospective, single-center and open-ended study in patients over the age of 70 with treatment-naive diffuse large B-cell lymphoma (DLBCL). This study intends to explore a new treatment pattern using Pro-miniCHOP-like regimen and simultaneously evaluate its safety and efficacy for future clinical practice.

Timeline

Start
2023-01-04
Primary completion
2025-07-03
Completion
2026-07-03

Drugs

EvaluationDrugModalityDoseRoute
Subject Orelabrutinib Small molecule 150 mg Oral
Subject Pomalidomide Other / unclassified 4 mg Oral
Background Cyclophosphamide Other / unclassified 400 mg/m2 Intravenous
Background Dexamethasone Small molecule 10 mg Intravenous
Background Doxorubicin Other / unclassified 25 mg/m2 Intravenous
Background Doxorubicin liposome Unknown 15 mg/m2 Intravenous
Background Rituximab Monoclonal antibody 375 mg/m2 Intravenous
Background Vindesine Small molecule 2 mg Intravenous

Indications

diffuse large B-cell lymphoma