drugset / Trial / NCT05948267
The Effect of Ketamine - Dexmedetomidine Admixture (Ketodex) on Hemodynamic Stability During Anesthesia Induction in Adults.
RandomizedParallel-groupSingle-blindOther
Summary
The aim of our study to compare two different doses of Dexmedetomidine added to anesthetic dose of ketamine in the induction of general anesthesia in adult patients regarding the hemodynamic profile, adequacy of hypnosis, intubation conditions and recovery type. We hypothesize that the use of Ketodex during induction of general anesthesia will produce better control regarding the hemodynamic profiles and quality of intubation than propofol.
Timeline
- Start
- 2023-05-25
- Primary completion
- 2023-10-30
- Completion
- 2024-11-15
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Comparator | Dexmedetomidine | Other / unclassified | 0.3 ug/kg | Intravenous |
| Comparator | Dexmedetomidine | Other / unclassified | 0.5 ug/kg | Intravenous |
| Comparator | Ketamine | Small molecule | 1 mg/kg | — |
| Comparator | Propofol | Small molecule | 2 mg/kg | — |
| Comparator | Fentanyl | Other / unclassified | 1 ug/kg | — |
| Comparator | Lidocaine | Other / unclassified | 40 mg | — |
Indications
No indication recorded.