drugset / Trial / NCT05974501
Pre vs Post Block in Total Knee Arthroplasty (TKA)
RandomizedParallel-groupTriple-blindSupportive care
Summary
The purpose of this project is to determine if a change in patient reported pain, nausea and vomiting after total knee arthroplasty can be observed with the substitution of a post operative adductor canal block for a preoperative adductor canal block in the current established peri-operative pain protocol and if these changes lead to a decrease in opioid consumption (in morphine equivalents).
Timeline
- Start
- 2023-09-29
- Primary completion
- 2024-01-22
- Completion
- 2024-01-22
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Ropivacaine | Other / unclassified | 0.2 % | Other |
| Subject | Ropivacaine | Other / unclassified | 20 ml | Other |
| Background | Acetaminophen | Small molecule | 1000 mg | Oral |
| Background | Celecoxib | Other / unclassified | 200 mg | Oral |
| Background | Dexamethasone | Small molecule | 10 mg | Intravenous |
| Background | Meloxicam | Small molecule | 30 mg | Intravenous |
| Background | Oxycodone | Other / unclassified | 5 mg | Oral |
| Background | Pregabalin | Small molecule | 75 mg | Oral |