drugset / Trial / NCT06017167
Prophylaxis Against Postoperative Nausea and Vomiting After Laparoscopic Cholecystectomy
RandomizedParallel-groupDouble-blindTreatment
Summary
The aim of the study is to compare antiemetic effects between dexmedetomidine and ondansteron in the first group versus dexamethasone and ondansteron in the second group. The primary outcome in this study is incidence of postoperative nausea and vomiting after laparoscopic cholecystectomy. The secondary outcomes are: * The severity of post operative nausea and vomiting. * Use of rescue antiemetic drugs. * Postoperative pain and sedation.
Timeline
- Start
- 2022-09-15
- Primary completion
- 2023-09
- Completion
- 2023-10
Publications
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Comparator | Dexamethasone | Small molecule | 8 mg | Intravenous |
| Comparator | Dexmedetomidine | Other / unclassified | 0.5 ug/kg | Intravenous |
| Comparator | Ondansetron | Other / unclassified | 4 mg | Intravenous |