drugset / Trial / NCT06017167

Prophylaxis Against Postoperative Nausea and Vomiting After Laparoscopic Cholecystectomy

NCT06017167

Phase 2 Unknown 70 enrolled Tanta University
RandomizedParallel-groupDouble-blindTreatment

Summary

The aim of the study is to compare antiemetic effects between dexmedetomidine and ondansteron in the first group versus dexamethasone and ondansteron in the second group. The primary outcome in this study is incidence of postoperative nausea and vomiting after laparoscopic cholecystectomy. The secondary outcomes are: * The severity of post operative nausea and vomiting. * Use of rescue antiemetic drugs. * Postoperative pain and sedation.

Timeline

Start
2022-09-15
Primary completion
2023-09
Completion
2023-10

Drugs

EvaluationDrugModalityDoseRoute
Comparator Dexamethasone Small molecule 8 mg Intravenous
Comparator Dexmedetomidine Other / unclassified 0.5 ug/kg Intravenous
Comparator Ondansetron Other / unclassified 4 mg Intravenous

Indications