drugset / Trial / NCT06043323

A Phase II Study of Axicabtagene Ciloleucel, an Anti-CD19 Chimeric Antigen Receptor (CAR) Tcell Therapy, in Combination With Radiotherapy (RT) in Relapsed/Refractory Follicular Lymphoma

NCT06043323

Phase 2 Recruiting 20 enrolled M.D. Anderson Cancer Center
NaSingle-groupOpen-labelTreatment

Summary

To learn about the safety of a drug called axicabtagene ciloleucel given in combination with radiation therapy to patients with relapsed/refractory FL.

Timeline

Start
2024-01-08
Primary completion
2026-09-01
Completion
2028-09-01

Drugs

EvaluationDrugModalityDoseRoute
Subject Axicabtagene Ciloleucel Cell therapy Intravenous
Background Acetaminophen Small molecule Intravenous
Background Cyclophosphamide Other / unclassified Intravenous
Background Diphenhydramine Unknown Intravenous
Background Fludarabine Small molecule Intravenous
Background Prednisone Other / unclassified Intravenous

Indications